Ctrl Ctrl to open is great, but

It does not always work.
It seems to happen randomly, and then after a couple minutes, or less, it’s working again. The same behaviour occurs with the open shortcut key, which I set to Win+Shift+x

I only noticed this when I updated to the latest beta 5.00.2177

Any ideas what the problem could be?

Does it work if you press Ctrlx2 or Win+Shift+X again after Listary fails to pop up the first time?

No unfortunately. It refuses to acknowledge the shortcuts for a couple minutes, then works again.
I ran Listary not as administrator today, and the problem didn’t occur. May happen again, but fingers crossed that fixed it.